Chris Davis (Orioles): Since the outset of the 2012 season, the first baseman has used his power and patience to produce a .258/.350/.534 slash line against right-handers. Davis could drive in multiple runs when he visits hitter-friendly Yankee Stadium to face righty Nathan Eovaldi (4.50 ERA, 1.52 WHIP in 2015).
Jimmy Paredes (Orioles): One of baseball's most improved players, Paredes has hit .294 with 10 homers across 272 at-bats this season. He has the skills to improve on his lifetime .730 OPS against right-handers (.480 vs. lefties) at the expense of Eovaldi (career 1.40 WHIP).
Adam Jones (Orioles): The outfielder could be worth a notable acquisition cost in DraftKings contests when he brings his career .283/.320/.476 slash line against right-handers into a matchup with Eovaldi (career 4.15 ERA). Jones could be part of an Orioles stack with Davis, Paredes and second baseman Jonathan Schoop.
Anthony Rizzo (Cubs): Hitting .296 with 16 homers and 12 steals across 394 plate appearances this season, the first baseman could produce in multiple ways when he bats at hitter-friendly Great American Ball Park against rookie righty Raisel Iglesias (1.52 WHIP). Rizzo has posted a lifetime .846 OPS against right-handers that exceeds his .753 mark vs. lefties. He could also swipe a base against catcher Brayan Pena, who has thwarted six of 43 would-be basestealers this season.
Addison Russell (Cubs): The rookie second baseman has produced notable splits, with a .704 OPS against right-handers that exceeds his .455 mark vs. lefties. Russell could drive in multiple runs against the inexperienced Iglesias, who has posted a 5.90 ERA across 29 Major League innings.
Jason Kipnis (Indians): The second baseman could improve on his season-to-date .326 average and score multiple runs when he bats at hitter-friendly Miller Park against righty Matt Garza, who has struggled this season (5.55 ERA and a 1.55 WHIP). Of note: Kipnis owns a lifetime .812 OPS against right-handers that exceeds his .668 mark vs. lefties.
Brandon Moss (Indians): The outfielder has hit 90 of his 106 career homers against right-handers, and he could add to that total when he faces the struggling Garza at Milwaukee's homer-happy venue. Garza has been stung by the long ball this season, allowing 17 homers across 99 innings.
David Murphy (Indians): Murphy -- who has seen time in the cleanup spot against right-handers of late -- will bring a lifetime .803 OPS against right-handers (.656 vs. lefties) into a matchup with Garza (4.97 FIP in 2015). The outfielder could be part of an Indians stack that could include Kipnis, Moss and outfielder Michael Brantley.
Justin Bour (Marlins): The first baseman has produced pronounced career splits, with an .823 OPS against right-handers in comparison to a .572 mark vs. lefties. Bour could drive in multiple runs when he plays at homer-happy Chase Field to face righty Jeremy Hellickson, who has a 5.01 ERA since the outset of the 2013 season.
Christian Yelich (Marlins): Having compiled 15 of his 18 career homers and 34 of his 39 lifetime steals at the expense of right-handers, the outfielder is in position to contribute in multiple ways when he faces Hellickson at a hitter-friendly road venue. The right-handed hurler has struggled this season to the tune of a 5.04 ERA and a 1.37 WHIP.
Troy Tulowitzki (Rockies): As a big leaguer, the shortstop has fared best vs. left-handers (.322/.405/.562 slash line) and at his offense-inducing home park (.323/.395/.561 slash line). Hitting .318 this season, Tulowitzki may be poised to have a productive game at home against Rangers southpaw Matt Harrison (career 4.21 ERA, 1.40 WHIP).
Nolan Arenado (Rockies): With 24 homers and 70 RBIs across 336 at-bats this year, the third baseman has propelled himself to the top tier of fantasy options at his position. Arenado has the skills to improve on his career .874 OPS against left-handers and his lifetime .875 OPS at Coors Field when he faces Harrison. Since the outset of the 2013 season, injuries have limited the southpaw to 22 innings.
Prince Fielder (Rangers): The first baseman -- who is hitting .337 this season overall -- owns a career .965 OPS against right-handers (.800 vs. lefties). Fielder is primed to post a difference-making stat line when he ventures to hitter-friendly Coors Field to face Kyle Kendrick (5.94 ERA, 1.45 WHIP in 2015) and a Rockies bullpen that ranks last in baseball with a 4.54 ERA.
Michael Wacha (Cardinals): With a 2.93 ERA and a 1.10 WHIP this season, Wacha has proven to be the ace of the Cardinals' impressive rotation. The right-hander could continue to hold the opposition in check when he faces a White Sox lineup that ranks last in the Majors with 303 runs. Once he leaves the game, his quest for a win may be helped by a St. Louis bullpen that sits second in baseball with a 2.41 ERA.
Nathan Karns (Rays): Karns -- who owns a 3.63 ERA and an 8.6 K/9 rate this season -- is primed to excel when he faces a Phillies lineup that ranks last in the Majors in OPS against right-handers (.649) and 27th in runs (325).
Odrisamer Despaigne (Padres): Despaigne does not own impressive season-to-date statistics, but he has thrived at his pitcher-friendly home park during his big league tenure (2.96 ERA, .211 opponents' average). On Tuesday, he could be an economical second starter for DraftKings participants when he works at home against the Giants.
Brett Anderson (Dodgers): With a 3.17 ERA across 18 starts, Anderson has been a useful second arm for DraftKings participants this season. The left-hander could continue to compile effective innings when he works at pitcher-friendly Turner Field against a Braves lineup that ranks 29th in baseball with a .626 OPS vs. southpaws.
All statistics are accurate through the completion of Sunday's games.