The club decided not to have Pedroia play in Minor League rehab games leading up to his return Friday.
"The way he's feeling swinging the bat right now -- and I know it's BP and we've done some things in the cage to emulate a little bit more velocity -- we want him back in the lineup as soon as he's available," said Red Sox manager John Farrell.
Pedroia has been on the disabled list since June 25 with a right hamstring strain.
All-Star Brock Holt has been getting all the starts at second in Pedroia's absence.
Ian Browne is a reporter for MLB.com. Read his blog, Brownie Points, follow him on Twitter @IanMBrowne and listen to his podcast. This story was not subject to the approval of Major League Baseball or its clubs.