Danny Valencia replaced Donaldson at third base as the Royals came to bat in the sixth inning. Valencia wound up hitting a three-run homer in the ninth off Brandon Finnegan to break the game open.
"[Donaldson] has been sick, and then it was a tough day with the heat," Blue Jays manager John Gibbons said. "He was a little dehydrated."
Robert Falkoff is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.