Justin Bour (Marlins): With four homers in his past 19 at-bats, Bour is currently one of the hottest hitters in baseball. The first baseman could improve on his career .836 OPS against right-handers (.472 vs. lefties) when he vacates his pitcher-friendly home venue and heads to Fenway Park to face Red Sox righty Rick Porcello (6.08 ERA in 2015).
Dee Gordon (Marlins): From his perch atop the lineup, the second baseman could reach base often or score multiple runs when he brings his lifetime .698 OPS against right-handers (.645 vs. lefties) into a matchup with Porcello (career 4.45 ERA, 1.36 WHIP). Sitting second in the Majors with 29 steals, Gordon may get the green light if he reaches base.
Bryce Harper (Nationals): Hitting .344 with 25 homers and 60 RBIs, the outfielder could be worth a major expenditure in DraftKings contests on Wednesday. Harper will bring a career .927 OPS against right-handers (.774 vs. lefties) into a matchup with Reds rookie righty Michael Lorenzen (5.90 FIP).
Mitch Moreland (Rangers): The first baseman -- who has compiled 14 homers and 44 RBIs across 233 at-bats this season -- could improve on his career .797 OPS against right-handers (.648 vs. lefties) when he faces D-backs righty Jeremy Hellickson (5.02 ERA since 2013).
Jason Kipnis (Indians): With a .340 average and 56 runs across 377 plate appearances this season, the second baseman has been among the most productive players at his position. He may collect multiple hits and runs when he brings his career .812 OPS against right-handers (.676 vs. lefties) into a matchup with Astros righty Dan Straily (lifetime 4.60 ERA, 1.32 WHIP).
Brandon Moss (Indians): Moss has hit 89 of his 105 career homers against right-handers, and he could add to that total when he faces Straily, who has posted a career 1.4 HR/9 rate.
Paul Goldschmidt (D-backs): With a lifetime .330/.423/.606 slash line against left-handers, the first baseman has proven to be among the best in baseball during those matchups. Goldschmidt could improve on his season-to-date totals of 20 homers and 67 RBIs when he meets up with Rangers southpaw Matt Harrison, who will be making his first start of 2015 and just his seventh appearance since the outset of the 2013 season.
A.J. Pollock (D-backs): With 10 homers, 18 steals and 54 runs across 344 plate appearances, Pollock has been an asset to DraftKings participants on many occasions this season. The outfielder could thrive when he puts his lifetime .847 OPS against left-handers (.750 vs. righties) on the line against Harrison (career 4.15 ERA, 1.40 WHIP).
Nick Ahmed (D-backs): The shortstop could excel when he brings his career .760 OPS against left-handers (.580 vs. righties) into a matchup with Harrison. As a big leaguer, the southpaw has allowed right-handed batters such as Ahmed to post a .781 OPS (.689 OPS allowed to lefty hitters). Ahmed could also excel late in the game against a Rangers bullpen that sits 29th in baseball with a 4.36 ERA.
Josh Donaldson (Blue Jays): The third baseman will bring a lofty lifetime .297/.374/.589 slash line against left-handers into a matchup against White Sox southpaw John Danks (career 4.32 ERA, 1.34 WHIP). Donaldson could be part of a productive lineup on Wednesday, as the Blue Jays lead the Majors by a wide margin with an .860 OPS vs. lefties.
Russell Martin (Blue Jays): The catcher could provide production at a premium position when he puts his lifetime .803 OPS against left-handers (.742 vs. righties) to the test against Danks (4.95 ERA in 2015). Of note: Martin and his teammates will attempt to put balls into play against a White Sox defense that ranks last in the Majors with a .663 defensive efficiency ratio.
Albert Pujols (Angels): With 17 homers across 128 at-bats since May 28, Pujols is a prime candidate to rip a roundtripper when he brings his career .318/.410/.609 slash line against left-handers into homer-happy Coors Field to face lefty Chris Rusin (career 4.76 ERA, 1.50 WHIP).
David Freese (Angels): As a big leaguer, Freese has thrived against left-handers to the tune of an .836 OPS (.733 vs. righties). He could excel when he vacates his pitcher-friendly home park to face Rusin at offense-inducing Coors Field. In his career, Rusin has allowed right-handed batters such as Freese to post an .857 OPS (.683 OPS allowed to lefty hitters).
Clayton Kershaw (Dodgers): The left-hander -- who has produced a 2.07 ERA since the outset of the 2013 season -- is by far the most skilled starter on the Wednesday evening docket. Kershaw could turn in a dominant start when he works at his pitcher-friendly home park against a Phillies lineup that ranks last in the Senior Circuit with 292 runs.
Trevor Bauer (Indians): Bauer could improve on his season-to-date 8.6 K/9 rate when he works at his home park against an Astros lineup that leads the Majors with 797 strikeouts. The right-hander could also come away with a win if his supporting cast has success against Straily.
Michael Wacha (Cardinals): The right-hander -- who has registered a 2.66 ERA and a 1.09 WHIP this season -- could accumulate several quality frames and strikeouts when he faces a Cubs lineup that ranks second in the Majors with 744 whiffs. Once he leaves the game, Wacha may be well-supported by a St. Louis bullpen that sits second in baseball with a 2.14 ERA.
Charlie Morton (Pirates): Morton could be an economical second starter in DraftKings when he works at his pitcher-friendly home park against a Padres lineup that ranks 26th in baseball with a .664 OPS against right-handers. Also in his favor: Morton's chances for a win will likely be supported by a Bucs bullpen that sits third in baseball with a 2.53 ERA.
All statistics are accurate through the completion of Monday's games.