The players listed below could provide difference-making stats for DraftKings participants on Tuesday.
Chris Davis (Orioles): As a big leaguer, the first baseman has produced an .844 OPS against right-handers that exceeds his .740 mark vs. lefties. Hitting at homer-happy Camden Yards, Davis could put a ball into the outfield seats when he faces Rangers righty Colby Lewis (career 4.77 ERA, 1.38 WHIP).
Chris Parmelee (Orioles): Since being recalled on June 16, Parmelee has hit .302 with four homers across 43 at-bats. The outfielder could be an economical option for DraftKings participants when he faces Lewis, who in his career has allowed left-handed batters such as Parmelee to post an .824 OPS (.721 OPS allowed to righty batters).
Travis Snider (Orioles): Snider may have balanced lifetime splits, but he has smacked 45 of his 53 career homers against right-handers. The outfielder could drive in multiple runs when he faces Lewis, who has a 4.10 ERA this season. Snider could also thrive against a Rangers bullpen that ranks 29th in the Majors with a 4.38 ERA.
Jay Bruce (Reds): With a lifetime .813 OPS against right-handers (.734 vs. lefties), the outfielder could rip a round-tripper at his hitter-friendly home park against Twins fly-ball-prone righty Phil Hughes (career 1.2 HR/9 rate).
Brayan Pena (Reds): Pena could provide economical production at a premium position when he brings his lifetime .692 OPS against right-handers (.584 vs. lefties) into a matchup at his offense-inducing home park against Hughes (4.42 FIP in 2015).
Jose Altuve (Astros): With a lofty lifetime .345/.388/.475 slash line against left-handers, the second baseman has proven to be among the best in baseball during those matchups. Altuve could reach base often or score multiple runs when he hits at home against Royals southpaw Danny Duffy (5.44 ERA, 1.70 WHIP in 2015).
Carlos Correa (Astros): Since being recalled on June 8, Correa has excelled against left-handers to the tune of a .967 OPS (.896 vs. righties). The shortstop could produce a notable stat line when he faces Duffy, who in his career has allowed right-handed batters such as Correa to post a .768 OPS (.609 OPS allowed to lefty hitters).
Billy Butler (A's): Butler has produced pronounced lifetime splits, with a .901 OPS against left-handers in comparison to a .763 mark vs. righties. The slugger could drive in multiple runs against Rockies southpaw Jorge De La Rosa, who in his career has allowed right-handed batters such as Butler to post a .794 OPS (.643 OPS allowed to lefty hitters). Butler could also thrive late in the game against a Rockies bullpen that ranks last in baseball with a 4.72 ERA.
Marcus Semien (A's): Having compiled six homers and seven steals across 310 plate appearances, Semien has helped DraftKings participants some this season. On Tuesday, the righty-hitting shortstop could improve on his lifetime .728 OPS against left-handers (.678 vs. righties) at the expense of De La Rosa (career 4.63 ERA, 1.44 WHIP). Also of note: Semien and his teammates will attempt to put balls into play against a Rockies unit that ranks 24th in baseball with a .677 defensive efficiency ratio.
Josh Donaldson (Blue Jays): The third baseman could improve on his lofty lifetime .301/.378/.596 slash line against left-handers when he meets up with Red Sox rookie southpaw Eduardo Rodriguez at homer-happy Rogers Centre. Donaldson could be part of a high-scoring lineup, as the Blue Jays lead the Majors by a wide margin with an .872 OPS against lefties.
Kevin Pillar (Blue Jays): In his first season as a starting outfielder, Pillar has compiled six homers, 12 steals and 41 runs across 299 plate appearances. With a career .708 OPS against left-handers (.654 vs. righties) and set to face Boston's Rodriguez, he could join a Blue Jays stack with Donaldson, Jose Bautista and Edwin Encarnacion.
Prince Fielder (Rangers): The first baseman -- who is hitting .351 across 288 at-bats this season -- could improve on his career .967 OPS against right-handers (.802 vs. lefties) when he meets up with Orioles fly-ball-prone righty Miguel Gonzalez (career 1.3 HR/9 rate).
David Peralta (D-backs): Peralta has produced lopsided career splits, with an .836 OPS against right-handers in comparison to a .503 OPS vs. lefties. The outfielder could drive in multiple runs when he bats at his offense-inducing home park against Dodgers righty Carlos Frias (career 4.92 ERA, 1.42 WHIP).
Cole Hamels (Phillies): With an ERA between 2.46 and 3.60 in each season since 2010, the left-hander has been the model of a consistent ace. Hamels could compile strikeouts and quality frames when he faces a Brewers lineup that ranks 28th in the Majors with a .647 OPS against southpaws.
Ian Kennedy (Padres): Having allowed eight earned runs across his past five starts, Kennedy has righted the ship after an inconsistent start to the season. The right-hander could be a cost-effective option for DraftKings participants when he works at his pitcher-friendly home park against a Mariners lineup that ranks 28th in baseball with a .655 OPS against righties.
Chris Sale (White Sox): With a 103-to-11 strikeout-to-walk ratio across his past nine starts, Sale has shown that he can sustain the level of dominance that led to a 2.17 ERA and a 0.97 WHIP a year ago. The left-hander could excel when he heads to the National League to face a Cardinals lineup that sits 24th in the Majors with a .676 OPS against southpaws.
Danny Salazar (Indians): With 284 strikeouts across 239 2/3 career innings, the right-hander is the type of high-upside hurler that DraftKings participants seek for contests with a large number of entrants. Salazar could compile several whiffs and quality frames at pitcher-friendly Tropicana Field, where he will face a Rays lineup that ranks 21st in baseball with a .685 OPS against righties.
All statistics are accurate through the completion of Sunday's games.