Freeman received an injection during the game and is expected to miss Thursday's series finale. He is hoping to be ready for the start of the Mets series on Friday.
Freeman initially sustained the injury on a swing during an at-bat against the Mets on Saturday -- the same at-bat in which he drove in Jace Peterson and tied the game at 3 in the ninth inning, before the Braves went on to win 5-3.
"If you guys noticed, the swing before that, it was a funky, weird, twist-turn foul-off swing," Freeman said after Wednesday night's game. "Shot of pain right there, and I just tried to play through it, tried to gut it out until Sunday, but I just couldn't make it."
Braves manager Fredi Gonzalez said that the team has been managing the injury since it occurred.
"We've been trying to monitor, not let him take BP, just get him loose. ... But today it bothered him," Gonzalez said. "That was the deal I made with him, I said, 'I'll let you play until I see that it starts bothering you, and when that happens then it'll be my call.'
"And today, it was worse. … We had our hand specialist here and we saw him, I think it's just day to day. Hopefully it calms down and we get him back in the lineup."
Freeman said that he was originally not going to play the day after he sustained the injury, but felt like he could gut it out until Monday's off-day. Had Freeman done so, he would have been able to get an injection without missing a game.
"I'm kind of stubborn in that area," Freeman said. "It takes a lot for me to come out of a game and not play in a game. I got an injection after I came out of the game [tonight] so I will probably be missing tomorrow and hopefully be back Friday."
After going hitless in three plate appearances on Wednesday, Freeman is hitting .299 with 12 home runs, 43 runs scored and 41 RBIs.