Perez and Griffey were teammates on the 1975 and '76 "Big Red Machine" World Series champion teams. Perez, a native of Camaguey, Cuba, will manage the World Team and Griffey will manage the U.S. Team.
The event, in its 17th year, pits the top Minor League prospects as part of All-Star weekend. The U.S. team leads the all-time series, 10-6.
MLB Network will exclusively televise the game, and MLB.com will live stream the contest at 3 p.m. ET, with Matt Vasgersian, Dan Plesac, Heidi Watney and MLB.com's Jonathan Mayo on the call.
Tickets are available by visiting www.allstargame.com or the Reds box office at Great American Ball Park.
Joey Nowak is a reporter for MLB.com. Follow him on Twitter at @joeynowak This story was not subject to the approval of Major League Baseball or its clubs.