Josh Donaldson (Blue Jays): The third baseman could make strides on an already impressive career .301/.379/.596 slash line against left-handers when he faces White Sox lefty John Danks (career 1.33 WHIP) at hitter-friendly Rogers Centre. Donaldson could be part of a productive lineup, as the Blue Jays lead the Majors by a wide margin with an .862 on-base plus slugging percentage against left-handers.
Edwin Encarnacion (Blue Jays): Since the outset of his breakout 2012 season, Encarnacion has compiled a .282/.390/.550 slash line against lefties and a .272/.374/.549 slash line at Rogers Centre. The first baseman could drive in multiple runs at his offense-inducing home park against Danks, who has posted a 4.90 ERA since the start of 2012.
Danny Valencia (Blue Jays): Valencia could be an economical part of a Blue Jays stack alongside high-priced stars such as Donaldson and Encarnacion. He carries second- and third-base eligibility in DraftKings contests, and he has posted a lifetime .877 OPS against southpaws (.618 vs. right-handers).
Kevin Pillar (Blue Jays): Because he has registered a career .675 OPS against left-handers (.583 vs. righties), Pillar could finish off a Blue Jays stack against Danks. Additionally, the outfielder could swipe his eighth base of the season, as he has been caught only once in his eight attempts so far in 2015.
Zack Cozart (Reds): Cozart -- who has hit .272 with six homers this season -- could improve on his career .719 OPS against left-handers (.638 vs. righties) at the expense of lefty Chris Rusin (career 4.97 ERA). The shortstop could also benefit from facing a Rockies defense that ranks 28th in the Majors with a .665 defensive efficiency ratio this season.
Paul Goldschmidt (D-backs): The superstar first baseman wields an especially potent bat when facing left-handers, against whom he has posted a lifetime 1.033 OPS (.879 vs. righties). Goldschmidt could flash his power when he faces Cardinals lefty Jaime Garcia, who has been healthy enough to make just 17 starts since the start of the 2013 campaign.
Eric Hosmer (Royals): The first baseman is off to a great start this season, with a .311 batting average, seven homers and 30 RBIs. Hosmer could continue to thrive when he vacates his spacious home park to hit at homer-happy Yankee Stadium against righty Adam Warren (career 1.32 WHIP). During his career, Hosmer has posted a .796 OPS against right-handers, in comparison to a .681 mark vs. lefties.
Mark Teixeira (Yankees): The first baseman could reach base often or drive in multiple runs at hitter-friendly Yankee Stadium when he carries his career .914 OPS against left-handers (.868 vs. righties) into a matchup with Royals lefty Jason Vargas (career 1.32 WHIP).
Chris Davis (Orioles): During his career, Davis has posted an .843 OPS against right-handers (.730 vs. lefties) and an .889 OPS at Camden Yards. Thus, the first baseman could display his power at his cozy home park against Astros righty Scott Feldman (lifetime 4.51 ERA, 1.36 WHIP).
Jimmy Paredes (Orioles): Because many attractive aces are on the Tuesday docket, DraftKings participants could consider adding economical hitters such as Paredes. The third baseman -- who is hitting .344 with six homers across 125 at-bats this season -- will look to improve on his lifetime .742 OPS against right-handers (.478 vs. lefties) at the expense of Feldman (5.17 ERA in 2015).
Colby Rasmus (Astros): Rasmus has ripped 99 of his 124 career round-trippers against right-handers, and he could add to that total on Tuesday, when he faces fly ball-prone righty Chris Tillman (career 4.57 FIP, 1.32 WHIP) at homer-happy Camden Yards.
Luis Valbuena (Astros): The third baseman -- who also qualifies at second base in DraftKings contests -- has posted an .801 OPS against right-handers since the outset of the 2014 season (.562 vs. lefties). He could go deep against Tillman, who has registered a lifetime rate of 1.3 homers per nine innings.
David Price (Tigers): The ace lefty could improve on his impressive career 3.21 ERA and 1.15 WHIP when he faces an A's lineup that ranks 29th in the Majors with a .585 OPS against southpaws. Price may also benefit from pitching at spacious O.co Coliseum.
Madison Bumgarner (Giants): DraftKings participants could spend heavily on two lefty aces and pair Price with Bumgarner, who will oppose a Brewers lineup that ranks 27th in the Majors with a .638 OPS vs. lefties. With a career 3.05 ERA that incorporates a 2.84 mark across nine starts this season, the southpaw offers an outstanding combination of reliability and excellence.
Jacob deGrom (Mets): deGrom returned to his 2014 National League Rookie of the Year form (2.69 ERA) when he fanned 11 batters across eight scoreless innings on Thursday. The right-hander could have another outstanding outing on Tuesday, when he faces a Phillies lineup that ranks last in the Majors in runs per game (3.17) and 28th in OPS vs. righties (.630).
Danny Salazar (Indians): Because Salazar has accumulated 245 whiffs across 205 2/3 career frames, he could provide elite production for DraftKings participants who do not wish to allocate the necessary resources for Price and Bumgarner. The right-hander could compile quality frames when he faces a Rangers lineup that ranks 22nd in the Majors with a .676 OPS against righties.
All statistics are accurate through the completion of Sunday's games.