Victorino had missed the previous two games with calf soreness. The 34-year-old has fought to stay healthy this season, previously suffering a strained right hamstring that sent him to the 15-day disabled list last month, and he was a late scratch from Thursday's starting lineup because of issues with his calf.
"We'll evaluate him when he comes in [Sunday]," said Red Sox manager John Farrell. "Obviously he's day to day right now, but if there's anything more to that, we'll know in the morning when we check him out."
Betts remained in the game as the center fielder while Rusney Castillo moved over to right.
Victorino went 2-for-2 as a pinch-hitter in Wednesday's game vs. the Rangers, but Saturday marked his first starting nod in six days. Now hitting exclusively from the right side, he has primarily started against left-handers this season.
Alec Shirkey is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.