Joc Pederson (Dodgers): The outfielder has been wearing out right-handers this season, hitting them to the tune of a .954 OPS (.416 vs. lefties). On Sunday, Pederson could reach base often and score multiple runs against Rockies righty Kyle Kendrick (career 4.53 ERA, 1.37 WHIP).
Adrian Gonzalez (Dodgers): Gonzalez could improve on his career .303/.379/.535 slash line against right-handers at the expense of Kendrick, who has compiled a 7.65 ERA and a 1.58 WHIP in 2015. The first baseman could also drive in multiple runs, as the Dodgers have posted a Major League-leading .861 OPS against righties this season.
Andre Ethier (Dodgers): The left-handed-hitting outfielder could be part of a Dodgers-laden Sunday stack, as he has posted a lifetime .892 OPS against right-handers (.643 vs. lefties). In his career, Kendrick has allowed lefty hitters to compile an .827 OPS (.739 OPS allowed to righty batters).
Kyle Seager (Mariners): With a career .800 OPS against right-handers (.665 vs. lefties), the third baseman could reach base often against Red Sox righty Steven Wright. Across 45 career innings, the 30-year-old hurler has compiled a 1.42 WHIP.
Robinson Cano (Mariners): Cano could improve on his impressive career .319/.366/.524 slash line against righties at the expense of Wright on Sunday. With a 1.34 WHIP across 960 Minor League innings, Wright could struggle against Seattle.
Jason Kipnis (Indians): With a lifetime .796 OPS against right-handers (.653 vs. lefties), Kipnis could score multiple runs from the leadoff spot against Rangers righty Nick Martinez on Sunday. The second baseman has hit 38 of his 47 career homers against right-handers, and Martinez has accumulated a lifetime 4.64 FIP.
Michael Brantley (Indians): With a .349/.427/.560 slash line, the outfielder has been among the best hitters in the Junior Circuit this season. With a lifetime .788 OPS against right-handers (.708 vs. lefties), Brantley could reach base often at a hitter-friendly road venue against Martinez, who has posted a lifetime 1.39 WHIP.
Brandon Moss (Indians): On Sunday, Moss could be part of an Indians stack against Martinez at offense-inducing Globe Life Park in Arlington. The outfielder has ripped 83 of his 96 career homers against right-handers, which has aided in his producing a .795 OPS in those matchups (.734 vs. lefties).
Jose Altuve (Astros): Altuve is among the best in baseball against lefties, with a career .355/.397/.491 slash line against them. On Sunday, he could reach base often and score multiple runs against Blue Jays southpaw Mark Buehrle, who has posted a 1.38 WHIP since joining Toronto before the outset of the 2013 season.
Evan Gattis (Astros): With a lifetime .817 OPS against lefties (.744 vs. right-handers), Gattis could provide DraftKings participants with a productive catcher for his Sunday matchup with Buehrle. For his part, the slugger has registered 12 homers across 202 career at-bats against left-handers.
Ender Inciarte (D-backs): Inciarte has been receiving regular work out of the leadoff spot and could score multiple runs when he brings his career .723 OPS against right-handers (.660 vs. lefties) into an end-of-weekend matchup with Phillies righty Sean O'Sullivan (career 1.54 WHIP).
Paul Goldschmidt (D-backs): Goldschmidt has traditionally fared best against left-handers, but he has compiled an impressive career .877 OPS against righties. He could give DraftKings participants elite first-base production on Sunday when he faces O'Sullivan (career 5.86 ERA) at homer-happy Citizens Bank Park.
Joey Votto (Reds): With a career .980 OPS against right-handers (.883 vs. lefties), the first baseman could excel at his hitter-friendly home park against Giants 27-year-old righty Chris Heston, who has logged just 51 2/3 Major League innings.
Josh Collmenter (D-backs): The right-hander is coming off a rough start on Monday, but he carried a respectable 3.40 ERA into that outing. On Sunday, Collmenter could bounce back against a Phillies lineup that ranks last in baseball in runs per game (2.89) and OPS vs. righties (.596). If his Arizona teammates can score several runs, Collmenter could easily come away with a victory.
Collin McHugh (Astros): With a 3.50 ERA and a 1.19 WHIP, the right-hander is producing a strong follow-up to his 2014 breakout season (2.73 ERA, 1.02 WHIP). Set for a Sunday matchup against a Blue Jays lineup with several key hitters who fare best against southpaws, McHugh could receive ample run support if the opposing starter, Buehrle, cannot improve on his current 5.54 ERA.
A.J. Burnett (Pirates): The right-hander could have a tough time getting a win against Jake Arrieta on Sunday, but he could rack up whiffs against a Cubs lineup that leads the Majors with 344 strikeouts. A return to the Pirates has rejuvenated Burnett, who has compiled a 1.60 ERA and a 1.16 WHIP this season. On a day with few aces on the docket, DraftKings participants could be satisfied with several K's and quality frames from Burnett.
Scott Kazmir (A's): The owner of a 2.78 ERA and a 1.06 WHIP this season, Kazmir has held hitters to a .618 OPS when working at his spacious home park since joining the A's in 2014. On Sunday, the lefty could compile quality frames against a White Sox lineup that ranks last in the Majors with a .546 OPS vs. southpaws.
All statistics are accurate through the completion of Friday's games.