After the half-inning ended, Werth was seen talking to third-base coach Bobby Hensley and then manager Matt Williams before he came out of the game. Tyler Moore replaced Werth in left field.
X-rays of Worth's wrist were negative, according to Williams.
"We'll see how he responds [Saturday]," Williams said. "He took a pretty good one on the wrist."
Werth, who declined to comment, has had problems with his left wrist over the years. In 2012, he broke it while making a diving catch of a liner off the bat of then-Phillies infielder Placido Polanco and missed 12 weeks.
As a member of the Dodgers, he broke it and missed the entire 2006 season.
Bill Ladson is a reporter for MLB.com and writes an MLBlog, All Nats All the Time. He also can be found on Twitter @WashingNats. This story was not subject to the approval of Major League Baseball or its clubs.