Adam Jones (Orioles): With a career .799 OPS against right-handers that exceeds his .757 mark vs. lefties, the outfielder could reach base multiple times or rip a round-tripper against Rays righty Alex Colome. The 26-year-old hurler will be making his first 2015 start after posting a career 4.36 FIP and a 1.31 WHIP.Carlos Santana (Indians):
The first baseman with multi-position DraftKings eligibility could improve on his impressive lifetime .852 OPS against left-handers (.787 vs. righties) when he faces Blue Jays lefty Mark Buehrle
(career 1.29 WHIP).
Dee Gordon (Marlins): Gordon -- who has compiled a lifetime .701 OPS against righties (.604 vs. left-handers) -- could reach base often and swipe a bag when he faces Phillies righty Jerome Williams (career 1.36 WHIP).
Ike Davis (A's): Davis could excel against Rangers righty Colby Lewis at hitter-friendly Globe Life Park in Arlington. The left-handed-hitting first baseman has compiled a career .815 OPS against righties (.579 vs. southpaws), and Lewis has allowed left-handed batters to accumulate a collective lifetime .830 OPS.
Stephen Vogt (A's): Vogt is another left-handed hitter who could thrive against Lewis. The catcher is hitting .348 with four homers and 15 RBIs this season, and he owns a lifetime .757 OPS against right-handers (.628 vs. lefties).
Josh Reddick (A's): The outfielder could be part of an A's stack, as his career .763 OPS against right-handers (.691 vs. lefties) suggests that he could flash his power at a hitter-friendly venue against Lewis (career 4.81 ERA, 1.39 WHIP).
Andre Ethier (Dodgers): Multiple outfield injuries have opened up a starting role for Ethier, and with a lifetime .890 OPS against right-handers (.641 vs. lefties), he could be positioned for a strong performance against D-backs righty Rubby De La Rosa (career 4.38 ERA, 1.44 WHIP).
Adrian Gonzalez (Dodgers): The first baseman will look to carry a red-hot April (eight homers, 19 RBIs, .383 batting average) into May when he brings his lifetime .914 OPS against right-handers (.771 vs. lefties) into a matchup with De La Rosa.
Xander Bogaerts (Red Sox): The shortstop could excel at his hitter-friendly home park when he brings his lifetime .769 OPS vs. lefties (.624 against right-handers) into a matchup with Yankees southpaw CC Sabathia. The lefty hurler has compiled a 4.97 ERA since the outset of the 2013 season.
Hanley Ramirez (Red Sox): Ramirez has dazzled in a Boston uniform, recording 10 homers, 22 RBIs and a .293 batting average in 21 games. He has produced a career .925 OPS vs. lefties (.859 against right-handers), and he could smack a homer against Sabathia, who has surrendered 64 long balls across his past 72 starts dating back to 2012.
Buster Posey (Giants): Posey is one of the best hitters in baseball against lefties, with a career .966 OPS in comparison to an .812 mark vs. right-handers. He could provide DraftKings participants with plentiful production from the catcher position when he faces Angels lefty C.J. Wilson.
Carlos Carrasco (Indians): Carrasco could rack up the strikeouts when he opposes a Blue Jays lineup that possesses several sluggers who do their best work against southpaws. The right-hander has displayed tremendous swing-and-miss stuff, fanning 23 batters across 15 2/3 innings this season after racking up 140 whiffs in 134 frames a year ago.
Matt Harvey (Mets): With few aces on the docket, Harvey should attract plenty of attention from DraftKings participants, and for good reason. The right-hander has compiled a 2.45 ERA and a 0.98 WHIP as a big leaguer, and he will pitch at home against a Nationals lineup that is tied for third in the Majors with 185 strikeouts.
Tom Koehler (Marlins): The right-hander could improve on a lifetime 4.14 ERA and a 1.32 WHIP when he faces a Phillies lineup that ranks last in the Majors in runs scored (60) and OPS (.605). Koehler will also benefit from working at his pitcher-friendly home park, and he will likely carry a reasonable DraftKings price tag.
Scott Kazmir (A's): The left-hander has compiled a 0.99 ERA and a 0.88 WHIP this season, which represents an improvement on a respectable 3.55 ERA and 1.16 WHIP in 2014. Kazmir could thrive when he faces a Rangers lineup that ranks last in the American League with a .611 OPS. And with Lewis on the bump for the opposition, Kazmir could finish off a quality outing with a win.
Chris Heston (Giants): Heston struggled at homer-happy Coors Field his last time out, but he has allowed two earned runs across 14 2/3 innings at his pitcher-friendly home park since joining the team's rotation this season. The 27-year-old could be a cost-effective option for DraftKings participants when he pitches at home against an Angels lineup that will work without a designated hitter. The right-hander could be a late bloomer, as he produced a 3.38 ERA and a 1.17 WHIP in the hitter-friendly PCL last season.
All statistics are accurate through the completion of Wednesday's games.