SAN DIEGO -- Zack Greinke continued his mastery of the Padres on Friday night at Petco Park, allowing four hits in seven innings as the Dodgers picked up a 3-0 victory in an early season showdown between the top two teams in the National League West.
Greinke (3-0), who struck out seven while walking three, is 4-0 with 1.41 ERA against the Padres dating back to 2013.
San Diego starting pitcher Andrew Cashner (1-3) lost to Los Angeles for the second time this season. He allowed two runs on six hits and a walk over seven innings while striking out six. He has allowed two earned runs over his last 19 innings.
MOMENTS THAT MATTERED Loaded, unloaded: The Padres loaded the bases against Greinke in the second. Yonder Alonso walked and Will Middlebrooks and Derek Norris singled before an out was recorded, but Greinke worked himself out of trouble about as quickly as he got in it, striking out the next two hitters before getting Wil Myers on a line drive to second baseman Howie Kendrick.
"I didn't hit is as good as I could have with two strikes," Myers said. "But that cost us two runs." More >
One for Juan: With Dodgers manager Don Mattingly implying before the game that hot-hitting Alex Guerrero might get more playing time, starting third baseman Juan Uribe drove in his first run of the season with a second-inning single to cash in former Padres catcher Yasmani Grandal's double.
Taming Gonzo: Remember when Adrian Gonzalez hit three home runs off Cashner on April 8? Gonzalez didn't come close to doing as much on Friday night, bouncing into a double play in the first inning and striking out on a nasty slider in the third. In fairness, Gonzalez did single in the sixth inning, but Cashner kept him in the ballpark. More >
HR for CC: After striking out his first two at-bats, Carl Crawford figured out Cashner in the seventh inning, picking up his first home run of the season and only second RBI with a leadoff shot that doubled the Dodgers' lead.
"I just need to keep doing it," said Crawford. "Sometimes you get to scuffling and you try to do too much. That pitch was right down the middle and I just wanted to hit it hard."
"I don't think we'll anoint anybody. We'll keep matching up and put the best guy out there." -- Mattingly, when asked whether Yimi Garcia is his new closer
"We had one chance to break through and we just couldn't do it. He made some pitches. He's an All-Star pitcher. He's one of the best pitchers in the game, and it showed there. We just couldn't get the big hit." -- Padres manager Bud Black, on Greinke's escape in second
SOUND SMART WITH YOUR FRIENDS
Cashner has allowed two earned runs or fewer in 20 straight starts at Petco Park, a franchise-record streak that dates back to June 11, 2013. It is also tied for the longest active home streak in the Major Leagues with Jose Fernandez's current run at Marlins Park.
UPON FURTHER REVIEW
Black used a challenge in the third as Gonzalez reached first base after a strikeout and a throwing error by catcher Norris that pulled first baseman Alonso off the bag. Or did it? After a review, the call was overturned and Gonzalez was ruled out, ending the inning.
WHAT'S NEXT Padres:Ian Kennedy will be reinstated from the disabled list before making a start on Saturday at 5:40 p.m. PT against the Dodgers. Kennedy strained his left hamstring in his season debut on April 9. The right-hander was 0-3 in six starts against the Dodgers a year ago.
Dodgers:Brandon McCarthy gets the starting assignment for Los Angeles and is 5-1 with a 2.96 career ERA against San Diego. He is 2-1 in three career starts at Petco Park.
Corey Brock is a reporter for MLB.com. Keep track of @FollowThePadres on Twitter.
Ken Gurnick is a reporter for MLB.com. Keep track of the Dodgers @kengurnick on Twitter. This story was not subject to the approval of Major League Baseball or its clubs.