Uehara suffered a left hamstring strain in Spring Training that has kept him out of game action since March 16. He pitched in three Grapefruit League games before suffering the injury.
"We'll take it one outing at a time," said Red Sox manager John Farrell. "We're not ruling out the possibility that it could be after one outing."
What will the Red Sox look for from Uehara to determine if he needs just the one game in the Minors?
"How he feels in just pitching in a game situation," Farrell said. "This wasn't arm related; this was obviously hamstring related. So how confident he is with the aggressiveness and intensity of his delivery, that will have a lot to do with it."
Ian Browne is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.