Gio Gonzalez cruised through the Mets' lineup the first two times through the order until the Mets got on the board in the fifth with an RBI single by Ruben Tejada. John Mayberry Jr. hit a solo homer to left in the sixth, his fourth of the spring, and Gonzalez reached his pitch limit soon after.
Gonzalez, scheduled to be the Nats' No. 4 starter this year, completed 5 2/3 innings and allowed two runs on seven hits with six strikeouts and a walk.
"I'm ready to go," Gonzalez said. "I'm excited. I'm ready to break with the team and have some fun and get ready for the season to go."
The Mets and Nationals were involved in a trade together on Monday when left-hander Jerry Blevins was sent to New York for outfielder Matt den Dekker. Blevins was scratched from his appearance Monday, so he came into the game on Tuesday to face one batter, Bryce Harper. Blevins struck Harper out on three pitches.
"I would imagine that whoever the lefty is, Bryce will get those guys when appropriate," Nationals manager Matt Williams said. "A couple slow curveballs that Bryce didn't wait quite long enough for. He's never seen him in game competition. Live BP, maybe. But it's good for Bryce to get a sense of him, too, just in case."
Also on Tuesday, Max Scherzer threw 102 pitches in a Minor League game in his final tuneup before making the start on Opening Day for the Nationals.
Up next: Jordan Zimmermann will make his final Grapefruit League start when the Nationals travel to Jupiter, Fla., to take on the Marlins at Roger Dean Stadium on Gameday Audio. It is scheduled to be Zimmermann's final tuneup before he pitches in Washington's second game of the season against the Mets. He has a 1.37 ERA with 15 strikeouts in five Grapefruit League starts.
Jamal Collier is a reporter for MLB.com. Follow him on Twitter at @jamalcollier. This story was not subject to the approval of Major League Baseball or its clubs.