"I kind of picked the wrong day to give up fly balls," Nolasco said with a smile. "I'd been getting ground balls all spring, but gave up some fly balls today with the wind blowing. I just tried to limit the damage from there and get my work in."
But Nolasco got on track after that, retiring 10 in a row before allowing a leadoff single to Jonathan Schoop in the fifth inning. Schoop ended up coming around to score on a throwing error from Danny Santana with two outs.
Nolasco went six innings, giving up four runs (three earned) on five hits and two walks in his second-to-last outing of the spring.
He outlasted Orioles right-hander Miguel Gonzalez, who went 5 2/3 innings, surrendering five runs on seven hits and a walk. It was his first free pass issued this spring. The righty also struck out five.
"I did [settle in]," Gonzalez said. "Towards the end, [Chris] Tillman talked to me and told me I was throwing down a little bit on my offspeed, and then I speeded up and I felt a lot better. But the guys weren't getting good swings after the third inning, so I felt pretty good at the end."
The Twins got on the board with a two-run homer in the second from Fryer, who is competing for the backup catcher job with Josmil Pinto and Chris Herrmann.
Minnesota scored two more runs in the third, when Santana led off the frame with a single, stole second base and scored on a double from Eduardo Nunez. Nunez scored on a single from Kennys Vargas, but Vargas was thrown out at second trying to stretch it to a double.
After Gonzalez departed with two outs in the fifth and Vargas at first base after a one-out walk, reliever David Hess came in and served up a two-run blast to center to Arcia to give the Twins a 6-4 lead.
Twins right-hander Tim Stauffer gave up a solo homer to Mike Yastrzemski to lead off the bottom of the eighth and make it 6-5.
Up next: The Orioles will travel to Port Charlotte, Fla., on Monday to face Tampa Bay at 1:05 p.m. ET, with O's No. 4 prospect Zach Davies making his first career Grapefruit League start. Wei-Yin Chen, who will likely face the Rays in next week's season-opening series, will pitch in a Minor League game instead.