The band's platinum hit "Centuries" -- apropos for a ballpark in its second century and a game in its third -- also will be televised live to a national audience on "Baseball Tonight," airing at 7 ET on ESPN2. That will be immediately followed by the live broadcast of the Opening Night game at 8 ET.
Then comes Opening Day on April 6 for all other 28 teams.
"Wrigley Field has always been a magical place to me," said Pete Wentz, Fall Out Boy's bassist. "In some ways I can chart milestones of my life and growing up there -- from going to see Andre Dawson and Ryne Sandberg play, to going with the my dad to one of the first night games they ever had there, to the first time I took the 'L' there on my own for a game with my friends. When our band all lived in an apartment together in Roscoe Village, we used to pass out fliers for shows at the Metro after games. It has been a lifetime dream to get the chance to play at Wrigley Field. We are grateful to MLB for the opportunity and so excited to perform for our hometown crowd."
In addition to "Centuries," Fall Out Boy will perform its newest single "Uma Thurman" as well as the multiplatinum hit "My Songs Know What You Did in the Dark [Light 'em up]."
Fall Out Boy won "Best Alternative Band" at the 2014 People's Choice Awards. Their sixth studio album, "American Beauty/American Psycho," debuted at No. 1 on the Billboard Top 200 and peaked at No. 1 on iTunes in more than 22 countries upon its release in January. The band also has written the song "Immortals," featured in the Oscar-nominated Disney movie "Big Hero 6."
With Fall Out Boy's performance taking place before the game, batting practice for the Cubs and Cardinals will be moved earlier by approximately 30 minutes. Gates at Wrigley Field will open at 4:35 p.m. CT as a result.
Mark Newman is enterprise editor of MLB.com. Read and join other baseball fans on his MLB.com community blog. This story was not subject to the approval of Major League Baseball or its clubs.