"I'm excited for this moment, and I'm really happy for my first base hit in the Majors," Quintana said. "I'm happy about [my start]. All my stuff's working good. Every start, I have more confidence, all my pitches."
For the Reds, Todd Frazier homered off of White Sox closer David Robertson, who continued to struggle this spring. Frazier put the Reds in front in the second inning when he led off with a single and later scored on an error by second baseman Emilio Bonifacio.
But the White Sox grabbed the lead right back, capitalizing on the erratic Jason Marquis. After Marquis issued a pair of walks, Alexei Ramirez doubled into the left-field corner, scoring both runners, before being thrown out trying for a triple.
Marquis, who figures to have earned a spot in the starting rotation now that Paul Maholm and Tony Cingrani are destined for the bullpen, allowed four runs in five innings. He looked good early, but labored as the game progressed, walking three in his final two frames.
"I didn't anticipate him shutting out the Cactus League," Reds manager Bryan Price said of Marquis, who entered the game having allowed one run in three starts. "He just wasn't as sharp today. His ball was coming back. He was missing his lanes with his sinker a little bit. He still got a bunch of ground-ball outs. When he was in the zone, he was typically pretty good."
For the White Sox, Beckham had a two-run homer and pair of doubles. He began the day just 1-for-22 in Cactus League action. Bonifacio notched a hit and a walk, but he committed a pair of errors. Geovany Soto and Courtney Hawkins added solo home runs.
Marlon Byrd added two hits for the Reds, bringing his spring batting average to .381. Chad Wallach had a sac fly in the seventh to pull the Reds to within a run at 5-4.
Up next: With news that Cingrani and Maholm will be working out of the bullpen, it appears as though Anthony DeSclafani has won a rotation spot on the Reds' Opening Day roster. He has three spring starts remaining, and one of those comes Thursday against the Rangers at Goodyear Ballpark. J.J. Hoover and Jumbo Diaz are among the pitchers set to follow DeSclafani. The 4:05 p.m. ET contest can be heard via a free reds.com webcast.