"I am a decision maker on that one," Manfred said, "and I just don't think it's appropriate [to comment]."
Hamilton is facing a likely suspension for what sources say was a drug-related relapse that occurred late in the offseason, making this his first such transgression since getting reinstated by MLB in June, 2006.
The Angels outfielder has spent the spring rehabbing from Feb. 4 surgery to his right AC joint and wasn't issued a locker at Tempe Diablo Stadium.
There's still no word on when a decision could come down.
"All I can say to you about the timing is that because Josh isn't in position to be on the field, it has made the timing a little more relaxed than if we had the circumstance of somebody on the field," Manfred said. "Beyond that, I just can't say any more."
MLB.com reporter Ken Gurnick contributed to this story.
Alden Gonzalez is a reporter for MLB.com. Read his blog, Gonzo and "The Show", and follow him on Twitter @Alden_Gonzalez. This story was not subject to the approval of Major League Baseball or its clubs.