Meyer would go on to strike out Sierra and Matt Holliday before inducing a groundout to second to end the threat. He tossed two scoreless innings, permitting two hits with one walk and two strikeouts.
In his first spring outing on Monday, Meyer let the stakes -- facing Pirates All-Star outfielder Andrew McCutchen -- affect him. Though he didn't give up a run over 1 2/3 innings, he did hit a batter, walk another two and throw a wild pitch.
This time around, Meyer avoided getting too amped up for the occasion and remained poised. Even during his first inning of work, he worked around a leadoff single.
"I felt better today," Meyer said. "I made some pitches when I needed to. Continuing to work on getting better and getting guys out."
"It was a lot more fun today than it was the other day," Meyer said. "That's what it's all about. Just go out there and have some fun, enjoy yourself. We're in a special environment where it's a good opportunity for everybody."
Added manager Paul Molitor: "Meyer did good. He faced some good hitters in some tough situations. It seemed like he had a little extra when he needed it."
Third baseman Miguel Sano, the organization's second-best prospect, blasted his second homer of the spring -- a two-run shot deep to left off lefty Tyler Lyons in the sixth.
"I haven't figured that one out either," Molitor said of whether it was further than the previous Sano dinger. "I don't think he got it all, either. That's the funny part. Stayed back on a changeup, and we all know he's a strong man. The wind probably pushed it a little farther than it should, but I still think it had plenty of distance."
Christina DeNicola is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.