By the time Ferrell entered the game in the top of the seventh for the D-backs, the Reds were already up 9-1.
Reds starter Mike Leake looked ready for the regular season to begin as he allowed just two hits in three scoreless innings.
Meanwhile, Allen Webster, who is trying to win a spot in the Arizona rotation struggled. The right-hander allowed three runs in the first and another in the third before being taken out with one out in the frame.
Brayan Pena and Todd Frazier each collected three RBIs apiece for the Reds.
Steve Gilbert is a reporter for MLB.com. Read his blog, Inside the D-backs, and follow him on Twitter @SteveGilbertMLB. This story was not subject to the approval of Major League Baseball or its clubs.