"You know what, I don't think it matters what ballpark, I think he's a good hitter," Francona said. "I think it was nice to see some of his old friends. They obviously have a lot of affection for him. We're starting to have a lot of affection for him when he starts banging those balls off the monster and hitting homers."
Oakland's own designated hitter, Billy Butler, also homered -- his second of the spring -- and outfielder Billy Burns contributed with an RBI single for the A's, who got three solid innings from rotation candidate Kendall Graveman.
The young right-hander allowed one run on two hits with one walk and one strikeout in his second Cactus League start, getting through three innings and throwing just 32 pitches in the efficient outing.
Indians starter Danny Salazar was responsible for Butler's home run but gave up just one other hit in 1 2/3 innings, despite two unearned runs scoring in his time on the mound.
Like Moss, Cleveland third baseman Lonnie Chisenhall also finished with two hits.
Up next: With American League Cy Young winner Corey Kluber taking his regular turn by pitching a simulated game in Indians camp Thursday, left-hander Nick Maronde will make the start for the Tribe in its game against the Royals at Goodyear Ballpark. Among the position players expected to be in the lineup, Michael Bourn looks to follow up on a 3-for-3 day at the plate his last time out on Tuesday.
Jane Lee is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.