Ferrell's multifaceted performance will be taped by HBO for an upcoming special and covered on social media using #FerrellTakesTheField. MLB.com also will provide extensive coverage of Ferrell's big day.
This isn't just another of Ferrell's comedy routines. His project will raise funds for groups involved in the fight against cancer, including Cancer for College and Stand Up To Cancer. Ferrell's game-used equipment will be auctioned off to help each cause.
Ferrell is also honoring Bert Campaneris, the former Major Leaguer who played all nine positions in a game 50 years ago.
Commissioner Rob Manfred said in a statement: "Spring Training affords an appropriate setting where our game can serve as the backdrop for an event that will benefit organizations that fight cancer. Will is a big fan of our game, and many of us in baseball -- among our clubs, players and our millions of fans -- are big fans of his. Major League Baseball is happy to take part in what will surely be a fun and memorable day for a great cause."
Of Ferrell's appearance, Giants manager Bruce Bochy said, "I'm not sure what the whole scenario is, but we'll have fun with it." Bochy is accustomed to dealing with celebrities on his roster, having managed the Padres when musician Garth Brooks spent Spring Training with them in 1998 and '99.
"He was great," Bochy said. "It could be a slow game or a long game, like you've seen the last week, and fans would start chanting 'Garth, Garth.' You'd put him in there and they'd get excited. He could make a long game a little bit more fun. He was our secret weapon to get the crowd back into it."
Bochy expressed hope that Ferrell won't take his allotted at-bat against Madison Bumgarner, who's scheduled to start against the White Sox.
"You can't tell Bum to take it easy," Bochy said. "Bum'll give him his best stuff."
The Giants-White Sox exhibition is slated to be fourth on Ferrell's list, preceded by Mariners at A's, Cubs at Angels and Reds at D-backs. After the Giants-White Sox game, Ferrell will conclude his big day with the Dodgers-Padres contest.
Chris Haft is a reporter for MLB.com. Read his blog, Haft-Baked Ideas, and follow him on Twitter at @sfgiantsbeat. This story was not subject to the approval of Major League Baseball or its clubs.