The Phillies gave Greene a $1 million signing bonus as the 39th overall pick in the 2011 First-Year Player Draft, but he never played above Class A Lakewood in four Minor League seasons.
"I'm more disappointed for him," Phillies player development director Joe Jordan said. "I'd be disappointed if it was a 20th-round pick, but this is a different situation."
The Phillies never heard from Greene as Spring Training approached. He finally informed them that he had no plans to attend camp. It certainly sounds like his baseball career is finished, but Jordan would not say Greene has officially quit or retired.
Greene, 22, hit a combined .224 with eight home runs, 74 RBIs and a .638 OPS in the Phillies' system. He missed time because of a left wrist injury in 2014, but also missed time in 2012 and 2013 when he showed up to Spring Training out of shape.
The Phillies have not had a first-round supplemental pick make an impact at the big league level since Cole Hamels in 2002.
Todd Zolecki is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.