The Mariners face the D-backs on Saturday at Salt River Fields.
Cano, who is in the second year of a 10-year, $240 million contract, has gone 2-for-5 with a double in two games this spring.
Cano played five games for Estrellas De Oriente in the Dominican Winter League over the offseason, in part so he could play in front of his ill grandfather, who was able to come watch him in their hometown of San Pedro de Macoris.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.