"His command wasn't great, but he got through a couple [innings], which was good," said manager Paul Molitor.
Pelfrey underwent surgery last June to decompress a nerve in his throwing elbow, limiting him to just five games in 2014. He began throwing bullpen sessions last September and made his first start of the spring in Saturday's game.
"It was good to see Mike out there," Molitor said. "He's waited a long time and put in a lot of work to get where he is."
Pelfrey was one of seven pitchers who combined to surrender 16 hits on Saturday. However, the team limited the damage by turning three double plays, two of which were when Pelfrey was on the hill.
Quinn Roberts is a reporter for MLB.com. Follow her on Twitter at @qlr5001. This story was not subject to the approval of Major League Baseball or its clubs.