GLENDALE, Ariz. -- Alexei Ramirez drove in three runs and Avisail Garcia slugged a pair of doubles as the White Sox opened the Cactus League season against the Dodgers on Wednesday with a 6-4 victory at Camelback Ranch.
The White Sox roughed up relievers Juan Nicasio for three runs in one inning and Carlos Frias for two runs in two innings.
Chicago starter Jose Quintana pitched two perfect innings with two strikeouts.
"It's time for preparation, throw good pitches, more strikes the first time," Quintana said. "The first hitter I was a little bit nervous because I wanted to throw a good pitch, but I feel really good. I threw the fastball in and out really good."
Former big league aces Brad Penny and Erik Bedard each pitched two innings and allowed one run as they try to make clubs as non-roster invitees.
Bedard started for the Dodgers and retired the first four Chicago batters, but he allowed the first of two Garcia doubles and an RBI single to Ramirez in the second.
The White Sox scored three runs in the third inning against Nicasio, with doubles by Adam LaRoche and Garcia.
Dodgers prospect O'Koyea Dickson homered off of Eric Surkamp in the sixth inning to cut the deficit to 6-2. Andre Ethier, who walked, scored on Kyle Jensen's double-play grounder in the seventh. Corey Seager plated a run in the ninth with a single.
Up next:John Danks gets the start Thursday, as the White Sox play their second straight game against the Dodgers to open Cactus League play at Camelback Ranch. Danks is working on a lower arm angle and lower leg kick as part of his refined delivery. Second base is a spot to keep an eye on, with Carlos Sanchez and Micah Johnson both playing in Wednesday's victory. Thursday's 2:05 p.m. CT contest will be broadcast live on a free whitesox.com video webcast, MLB.TV, MLB Network and Gameday Audio.
Ken Gurnick is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.